T. Rowe Price Biotech ETF

TDNA ETF

$24.32 +$0.91 (+3.88%) Price as of Oct 20, 2026 market close

Prices on SharpeShare since Sep 17, 2026

Range since Sep 17, 2026

Low $22.72High $25.59

Has TDNA beaten the S&P 500?

Since Sep 17, 2026 (to Oct 20, 2026), TDNA returned -4.6%; the S&P 500 (SPY) returned +1.1%.

Key figures vs the S&P 500

Return 
TDNA
-4.6%
S&P 500
+1.1%

Not annualized (under a year)

Largest decline 
TDNA
11.2%
S&P 500
2.0%
Risk-adjusted return 
TDNA
-1.43
S&P 500
0.82
Downside risk-adjusted return 
TDNA
-1.91
S&P 500
1.23

Sep 17, 2026 – Oct 20, 2026. Returns include dividends and other distributions, reinvested.

How are your investments doing?

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Returns by period

PeriodTDNAS&P 500
1 month -2.6% +1.0%

How has TDNA done each year?

SharpeShare can't compare a full calendar year of TDNA with the S&P 500 yet; the bars show the parts of years it can.

TDNA S&P 500 (SPY)
  • 2026*: TDNA -4.6%, S&P 500 (SPY) +1.1%

* Part of a year: the returns SharpeShare measures start or end inside it.

January February March April May June July August September October November December 2026

Select a month to see its return.

Each cell is that month's return, dividends included: green up, red down, uncolored when it rounds to 0.0%.

How rough does it get?

Counting dividends, TDNA's largest decline since Sep 2026 was 11.2%, from Sep 22 to Oct 16, 2026. It hasn't closed back at that high since. The S&P 500 didn't fall 10% or more in that time.

TDNA below its previous high S&P 500 (SPY)

Since Sep 17, 2026, TDNA moved less than 1% up or down on 39% of trading days. Its biggest one-day fall was 3.9% (Sep 23, 2026); its biggest rise 3.9% (Oct 20, 2026).

TDNA: share of days by daily move S&P 500 (SPY)

Highest closing price since Sep 2026: $25.59 on Sep 22, 2026. The latest close, $24.32 on Oct 20, 2026, is 5.0% below it.

How are your investments doing?

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